Targeted therapy is a specialized form of cancer treatment that uses drugs to target specific genes, proteins, or the tissue environment that contributes to cancer growth and survival. Unlike traditional chemotherapy, which affects both cancerous and healthy cells, targeted therapy focuses only on cancer cells, reducing damage to normal cells and minimizing side effects.
This approach is based on the unique genetic and molecular characteristics of a patient’s tumor. Targeted therapy blocks the growth and spread of cancer by interfering with specific molecules involved in tumor progression and survival, making it a powerful and more precise treatment option.
What does targeted therapy involve?
Targeted therapy involves advanced diagnostic tests to identify genetic mutations, abnormal proteins, or specific receptors on cancer cells. Once identified, specially designed drugs can block these targets to stop the cancer from growing, dividing, or spreading. It is commonly used in cancers such as breast cancer (HER2+), lung cancer (EGFR or ALK mutations), and leukemia.
- Inhibiting abnormal growth signals in cancer cells.
- Blocking the formation of blood vessels that feed tumors (anti-angiogenesis).
- Delivering toxic substances directly to cancer cells.
- Targeting hormone receptors in hormone-sensitive cancers.
- Disrupting the cancer cell's internal repair and survival pathways.
Signal Blockers
01
Anti-Angiogenesis Agents
02
Hormone Receptor Targeting
03
What Targeted Therapy treats
Oncologists trained in targeted therapy learn to interpret genetic and molecular test results and match patients with the most appropriate drug based on their tumor’s unique traits. They acquire expertise in the use of tyrosine kinase inhibitors, monoclonal antibodies, and combination therapies that specifically block cancer growth mechanisms. Targeted therapy has transformed treatment outcomes for many patients, allowing for more effective, less toxic, and highly personalized cancer care.